IPA-3 Size:10mg solid Smiles: CC1=CC=CC=C1CSC1=CC=C(N=N1)C1=CC=CC=N1
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IPA-3 Size:10mg solid Smiles: CC1=CC=CC=C1CSC1=CC=C(N=N1)C1=CC=CC=N1IPA 3 is a potent and selective PAK1 inhibitor. IPA 3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF B activation. IPA 3 treatment significantly inhibited the growth of HCC cells. The mechanisms through which IPA 3 treatment suppresses HCC cell growth are enhancement of apoptosis and blockage of activation of NF B. IPA 3 not only inhibits the HCC cell growth, but also suppresses the metastatic potential of HCC cells. Nude mouse
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