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In addition, 94.4% of patients in the tirzepatide group reached an additional 5% weight loss after randomization (another co-primary endpoint), compared to 10.7% in the placebo group over 72 weeks

(investor.lilly.com)

Tirzepatide is the established option with FDA approval, extensive clinical trial data, and growing real-world evidence supporting its efficacy in both type 2 diabetes and obesity