T-5224 Catalog No.:M8650-2 Epub 2014 Nov 21
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T-5224 Catalog No.:M8650-2 Epub 2014 Nov 21T 5224 is a selective inhibitor of c Fos activator protein 1. T 5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T 5224 has been investigated in phase II human clinical trials. T 5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP 1) is a pivotal transcription factor that regulates a wide range of cellular processes
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