CLC1B Polyclonal Antibody, 20ul Sample Library Tubes Facilitates T-cell receptor (TCR)-mediated GATA3

Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities

but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase

An important paralog of this gene is IFIT1

alpha 1 subunit

CLC1B Polyclonal Antibody, 20ul Sample Library Tubes Facilitates T-cell receptor (TCR)-mediated GATA3Natural killer (NK) cells express multiple calcium dependent (C type) lectin like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C type lectin like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000