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Phenobarbital-induced liver enlargement is associated with initial transient hyperplasia in rodents as an early event after treatment and a substantial proliferation of smooth endoplasmic reticulum, causing hepatocellular hypertrophy

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Kong B, Zheng X, Hu Y, Zhao Y, Hai J, Ti Y

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Single doses of beta-carotene (30 mg/kg) or mesozeaxanthin (50-250 mg/kg) given concurrently with a toxic acetaminophen dose reduced serum liver enzymes and in the case of mesozeaxanthin, microscopic evidence of liver tissue damage (Zahra 2010

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