KIRR1 Polyclonal Antibody, 100ul Sealing Film The protein encoded by HSP90AA1

The protein encoded by HSP90AA1 is an inducible molecular chaperone that functions as a homodimer heat shock protein 90 alpha family class A member 1 aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones

The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid| while metabolizing linoleic acid less effectively

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A mutation in this gene results in nonsyndromic mental retardation-3

KIRR1 Polyclonal Antibody, 100ul Sealing Film The protein encoded by HSP90AA1NEPH1 is a member of the nephrin like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size and charge selective ultrafiltration (Sellin et al., 2003