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L-Carnitine: L-Carnitine, an amino acid derivative, serves as a crucial cofactor in the transportation of fatty acids into the mitochondria, where they undergo oxidation to produce energy

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This posed a particular challenge to Novo Nordisks sales of its weight loss therapeutics, as did competition from Eli Lillys Zepbound, a glucose-dependent insulinotropic polypeptide and GLP-1 receptor, which performed better than Wegovy in terms of its ability to lower weight

Heerspink HJL, Parving HH, Andress DL et al (2019) Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial