PDE6D Rabbit Polyclonal Antibody, 20ul Protein Analysis The family members are characterized

The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids

The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family

FOXD3 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain

Mutations in TSC1 have been associated with tuberous sclerosis

PDE6D Rabbit Polyclonal Antibody, 20ul Protein Analysis The family members are characterizedThis gene encodes the delta subunit of rod specific photoreceptor phosphodiesterase (PDE) a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane bound PDE. In addition to its role in the PDE complex the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome 22. Alternative