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Animals were fasted for 2 hours prior to intraperitoneal injection of glucose (2 g/kg) +/- exendin-4 (1 nmol/kg) and continued to fast for 6 hours when blood glucose levels were assessed from the tail vein using a Contour glucometer (Bayer) and strips at 0-, 10-, 30-, and 60-minute time-points, with glucose response curves generated from these data

Well, there was no loss of lean mass and, if anything, lean mass trended upward from about 60.7 to 61.5 kg, which makes complete sense given that tesamorelin acts as a growth hormone secretagogue