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Semaglutide may contribute to lean mass loss without proper protein intake and resistance training

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The estimated mean change in body weight at week 68 was 20.4% with CagriSema versus 3.0% with placebo (a difference of about 17 percentage points), and more CagriSema participants reached weight-loss thresholds of 5%, 20%, 25%, and 30% than placebo

Caution is required when prescribing phentermine and it is not recommended for patients with a history of CVD, hypertension, or a history of cardiac arrhythmias or seizures