TEF-4 Polyclonal Antibody, 100ul Cellular Function Assays An inactivating nonsense mutation localized

An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9

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and a short C-terminal cytoplasmic domain that interacts with adaptor molecules

The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing

TEF-4 Polyclonal Antibody, 100ul Cellular Function Assays An inactivating nonsense mutation localizedThe Hippo pathway is an important evolutionarily conserved signaling pathway that controls organ size and tumor suppression by inhibiting cell proliferation and promoting apoptosis. An integral function of the Hippo pathway is to repress the activity of Yes associated protein (YAP), a proposed oncogene whose activity is regulated by phosphorylation and subcellular localization. When the Hippo pathway is turned off, YAP is phosphorylated and