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Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) PTM:May be proteolytically processed at

SKU: 5268837840

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Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) PTM:May be proteolytically processed atThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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Description

PTM:May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells

The ectodomain

and it associates maximally with the nucleotide-free states of these GTPases

RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors

Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) PTM:May be proteolytically processed atThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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