SFRP1 Polyclonal Antibody, 100ul Vessels Nonsyndromic hearing impairment is associated

Nonsyndromic hearing impairment is associated with a mutation in this gene

It has been suggested that defects in the human gene result in pipecolic acidemia

SLC39A1 encodes a member of the zinc-iron permease family

Overactivation of type I interferon secretion is linked to autoimmune diseases

SFRP1 Polyclonal Antibody, 100ul Vessels Nonsyndromic hearing impairment is associatedThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.