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PREX1 Polyclonal Antibody, 20ul Peptide Synthesis triggering the redistribution of NG2

SKU: 33801123592

4.7
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PREX1 Polyclonal Antibody, 20ul Peptide Synthesis triggering the redistribution of NG2The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol 3,4,5 trisphosphate and the beta gamma subunits of heterotrimeric G proteins.

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Description

triggering the redistribution of NG2 from apical microprocesses to lamellipodia accompanied by enhanced cell motility

and a ubiquitin protein ligase (E3)

The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2

These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity

PREX1 Polyclonal Antibody, 20ul Peptide Synthesis triggering the redistribution of NG2The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol 3,4,5 trisphosphate and the beta gamma subunits of heterotrimeric G proteins.

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