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David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, et al

A New England Journal of Medicine study published in 2021 found participants receiving GLP-1 drugs were more likely to show significant, sustained weight loss compared with those getting a placebo

Semaglutide is a once-weekly GLP-1 receptor agonist

20,21 Based on studies of genetically modified mice, considerable progress has been made in illustrating the functions of genes such as Mecp2 (Rett syndrome), Tsc1/2 (tuberous sclerosis), Fmrp (fragile X syndrome), Pten and Shank3 (PhelanMcDermid syndrome) in several monogenetic diseases