Tollip Polyclonal Antibody, 100ul Centrifuges Production of the surrogate light

Production of the surrogate light chain begins at the stage of pro-B cells

and two pseudogenes of this gene are also located on the long arm of chromosome 9

Heterozygous mutations in the this gene cause auditory-pigmentary syndromes

It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1

Tollip Polyclonal Antibody, 100ul Centrifuges Production of the surrogate lightTOLLIP encodes a ubiquitin binding protein that interacts with several Toll like receptor (TLR) signaling cascade components. The Toll interacting protein regulates inflammatory signaling and is involved in interleukin 1 receptor trafficking and in the turnover of IL1R associated kinase. Several transcript variants encoding different isoforms have been found for this gene.