LKB1(Phospho Thr189) Polyclonal Antibody, 100ul Antibody Humanization |Type IV collagen is the

|Type IV collagen is the major structural component of glomerular basement membranes (GBM)| forming a 'chicken-wire' meshwork together with laminins| proteoglycans and entactin/nidogen

The encoded protein may function as a tumor suppressor

kidney glomerulus and vascular smooth muscle

This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains

LKB1(Phospho Thr189) Polyclonal Antibody, 100ul Antibody Humanization |Type IV collagen is theThis gene, which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not