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ANPRB Polyclonal Antibody, 50ul General Lab Use Promotes TLR7 and TLR9-dependent production

SKU: 59075296674

4.3
EUR185.00 EUR217.00

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ANPRB Polyclonal Antibody, 50ul General Lab Use Promotes TLR7 and TLR9-dependent productionThis gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand binding domain, a single membrane spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C type

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Description

Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63-linked ubiquitination of IRAK1

The encoded protein controls the expression of several genes

|tissue specificity:Restricted to activated memory T-cells

tissue specificity:Testis

ANPRB Polyclonal Antibody, 50ul General Lab Use Promotes TLR7 and TLR9-dependent productionThis gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand binding domain, a single membrane spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C type

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