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It crosses the blood-brain barrier and activates the hepatocyte growth factor (HGF) / c-Met receptor pathway, a signaling system that governs neuron survival, synaptic formation, and neural circuit repair

[4], who attributed GLP-1RAs related cholelithiasis to the reduced cholycystokinine mediated gallbladder emptying and prolonged gallbladder refilling that may induce complicated cholelithiasis