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F 1.610.650.0170 ADEs may also be reported to the FDA: 1.800.FDA.1088 or www.fda.gov/medwatch Medical information: T 1.888.354.4855 (9:00 am 5:00 pm Eastern Time, Monday Friday) www.americanregent.com/medical-affairs For medical information outside of normal business hours that cannot wait until the next business day, please call 1.877.845.6371 About American Regent American Regent, Inc., a Daiichi Sankyo Group company, is a top-10 injectable manufacturer

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Improves Mood and Reduces Depression Vitamin B12 plays a significant role in the production of neurotransmitters such as serotonin and dopamine, which are essential for regulating mood

In addition to genetic predisposition, patients with insomnia report difficulty relaxing, feeling tense and anxious, being overly preoccupied with a myriad of thoughts, being worried and being depressed more frequently than control subjects