Topoisomerase II alpha(Phospho-Ser1469) Rabbit Polyclonal Antibody, 100ul Virus Packaging Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported

These exonucleases include the family of DNA polymerases

The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium

Alternative splicing results in multiple transcript variants encoding distinct protein isoforms

Topoisomerase II alpha(Phospho-Ser1469) Rabbit Polyclonal Antibody, 100ul Virus Packaging Several alternatively spliced transcript variantsThis gene encodes a DNA topoisomerase an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation chromatid separation and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another thus altering