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For cagrilintide , Phase 2 data has shown meaningful weight loss when used as monotherapy, and the CagriSema combination (cagrilintide plus semaglutide) has entered Phase 3 trials under the REDEFINE programme by Novo Nordisk

Women lost more weight than men (28.5% body weight loss vs 21.9% body weight loss, respectively) but both sexes saw dramatically superior results compared to anything produced by Tirzepatide or Cagrilintide monotherapy

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