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Less Common but Serious Side Effects Rare but serious risks may include: Gallbladder problems Pancreatitis Severe dehydration Low blood sugar (when combined with other diabetes medications) Medical supervision significantly reduces these risks

463 In addition, liraglutide can delay the formation of AS by inducing cell cycle arrest in vascular smooth muscle cells through the AMPK pathway

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Excess body fat can affect hormone production, so weight loss from GLP-1 medications may improve some hormonal imbalances related to carrying extra weight