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They can help regulate appetite, digestion, and blood sugar by communicating a signal of fullness to the brain, which may reduce hunger and lead to weight loss

Americans' voracious appetite for GLP-1 weight loss drugs has the nation on pace to spend more than $1 trillion on prescription drugs this year, a new report says

According to NICE Technology Appraisal 875 (TA875) , Wegovy (semaglutide) is available on the NHS only through specialist weight management services and for adults who meet specific criteria, including: Generally, a body mass index (BMI) of 35 kg/m or greater with weight-related comorbidities (with lower thresholds for certain ethnic groups) Referral to and engagement with a specialist weight management service (Tier 3) Treatment limited to a maximum of 2 years This differs from the broader marketing authorisation criteria in the SmPC, which includes adults with a BMI of 30 kg/m or greater, or 27 kg/m or greater with weight-related comorbidities