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(PubMed) George JD, Kim E, Spain R, Bourdette D, Salinthone S

Our findings establish GPR146 as a pleiotropic regulator of adipose tissue biology and a potential therapeutic target for MASLD

Targeted pharmacological interventions along these pathways have shown therapeutic promise in models of ischemic brain injury, neurodegeneration, and cancer

Most relevant peptides: KPV for skin and mucosal anti-inflammatory effects Thymosin alpha-1 for immune regulation (notably, the Pica study specifically included psoriatic arthritis patients) BPC-157 for tissue repair in joint involvement KPV is particularly relevant for psoriasis because of its calming effects on skin inflammation