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At day 5 the confluent cell layers were supplemented with cARLA cocktail

35 , e4788 (2022)

But on the specific question of which has been more rigorously studied in humans, SS-31 clearly leads

Hypersensitivity reactions are, most often, either immediate reactions (type I, e.g., anaphylaxis), occurring within an hour of exposure to the molecule, or delayed (type IV, e.g., contact dermatitis) reactions, which may manifest hours or even days after exposure