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Speaking on "The Pat McAfee Show" in May 2023, the 60-year-old said he started at 352 pounds and now weighs 290, and he hopes to reach 270 pounds

The anxiolytic effect was apparent as rats spend more time in open arms rather than closed arms

Possible signs of purging behavior include: Frequent trips to the bathroom right after meals Large amounts of food disappearing or unexplained empty wrappers and food containers Chronic sore throat Swelling of the salivary glands in the cheeks Dental decay resulting from erosion of tooth enamel by stomach acid Heartburn and gastroesophageal reflux Laxative or diet pill misuse Recurrent unexplained diarrhea Misuse of diuretics (water pills) Feeling dizzy or fainting from excessive purging behaviors resulting in dehydration Cuts and callouses on the knuckles can sometimes result from self-induced vomiting Individuals with bulimia can be slightly underweight, normal weight or overweight

Proc Natl Acad Sci U S A (1994) 91(15):73359.10.1073/pnas.91.15.7335 146 LorenzURavichandranKSPeiDWalshCTBurakoffSJNeelBG